Massimo Gadina

Massimo Gadina

Company: National Institute of Arthritis & Musculoskeletal & Skin Diseases

Job title: Chief, Translational Immunology Section


Dr. Massimo Gadina is currently the Director of the Office of Science and Technology at NIAMS. Prior to this appointment, he was a Senior Lecturer at the Division of Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, The Queen’s University of Belfast, Northern Ireland (UK). His research interests are focused on immune-mediated diseases and specifically to the biology of cytokines, their relative signaling pathways and the development of small molecules inhibitors of the JAK-STAT pathway. His translational work is also focused on autoinflammatory diseases as well as other inflammatory diseases.


Live Discussion & Question Time 10:00 am

Understanding major unmet clinical needs to identify logical expansion of research efforts and clinical expansion strategies for JAK inhibitors Discussing clinical data requirements and other evidence needed to inform research and product development strategies Collaborating with healthcare professionals and regulatory bodies to understand patient access landscapes and facilitate with strategic planningRead more

day: Day One

JAK Inhibitors as a Therapeutic Strategy for Inflammatory & Rheumatic Diseases 9:40 am

Reviewing the most recent findings related to JAK inhibitors’ mechanism of action and selectivity Discussing some of the diseases for which inhibition of the JAK-STAT pathway is proving to bea successful therapeutic approach or for which these drugs are actively investigated Outlining the effect of JAK inhibitors on circulating immune cells, in particular NK cells…Read more

day: Day One

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